Archive for the ‘generative disease’ Category
Reprogramming Pancreas Cells for Therapy
December 3rd, 2009 | 
Author: A group of biologists were doing experiments on rat pancreatic cells. This cell is believed similar to the cells at the early stages of diabetes.
Experiments led by Qiao Zhou of the of the Harvard Stem Cell Institute is expected to pave the way for regenerative medicine. ”In a sense, this way to reprogram cells,”explained another researcher, Douglas Melton, as quoted by Nature magazine.
In studies conducted over three years, the researchers several dozen viruses infect the rat pancreas. Each virus contains three genes that are active in pancreatic beta cells. These cells produce the hormone insulin. Once inserted, these viruses into cells of the pancreas and delivered three cargo gene. Three days later, the results appear. More than 20 percent of infected pancreatic cells into beta cells. Encouraging results than embryonic stem cells turn on specific networks.
Diabetes mellitus type one and type two suspected beta cell deficiency. If ordinary pancreas cells have been transformed into beta cells, these cells will give way to recovery for patients with diabetes. Therefore, insulin will be produced better.
”Only, reprogramming steps need to be tested in human cells for many years to know more about the effects,”confirm Melton.
Detection of heart with drop of blood
In a research report published over the Internet, Monday, in the journal Federation of American Societies for Experimental Biology (FASEB), they describe how the instrument can measure and collect the type of cells needed to build a network of blood vessels, called “endothelial progenitor cells “, by using only 20 microliter blood.
The development is also important because it allows scientists to collect the cells much more easily than with current techniques, so the effort to produce a network created in the lab for a heart by pass surgery a step closer to reality.
“This simple tool promising tool for pediatric and adult population in detecting, diagnosing, monitoring and providing treatment options for heart disease and blood vessel by using a bit of blood,” said study leader Shashi K. Murthy of the Department of Chemical Engineering at Northeastern Univerisity, Boston.
To collect the cells, the device operates in the same way with “Velcro” or magnet. In particular, the interior is coated with antibodies that bound only “endothelial progenitor cells”.
Blood flow through the device through the open funnel menyerupa (except blood coming through the narrow end and exit through the wide end), through the anti-body, and “endothelial progenitor cells are collected” in the process.
In addition to allowing researchers to collect cells from the blood very little, design a tool that gives researchers a new model to study the impact of blood flow in the body of the cell bonds – such as the clumping form in blood vessels.
“The most important is that this can become a new tool to assess cardiovascular health and blood vessels which cut the amount of blood necessary to issue through the end of the needle. Compact size makes it a great tool for use in developing countries, where access to medical laboratories no , “said Gerald Weissmann, Editor in Chief FASEB Journal, as reported China’s official news agency, Xinhua.
“In addition, this action was much closer to the future, where new blood vessels, veins and arteries for transplantation no longer necessary transplanted from the patient’s body. The amount of pain and recovery time for surgery ‘bypass’ will be reduced significantly, “he said.
Stress Increase Blood Sugar
It happened because when we are stressed, your body will adjust. This adjustment effort will lead to more rapid heart beat, and shortness of breath. Blood sugar had jumped the bandwagon.
“Under the pressure of stress, our bodies will be in fight mode, or let that blood sugar will rise as a form of preparation for this condition,” said Richard Surwit, PhD, author of The Mind Body Diabetes Revolution.
Basically, the stress hormones in our bodies are designed only to deal with stressful situations that are temporary, such as traffic, deal with employment tests, or to meet future in-laws, for example. Unfortunately, most of the stress we experience chronic, long settled alias. Call it a job that requires long hours every day, or must care for a sick parent.
As a result, stress hormones such as predators were going to have to endure long periods of time. Blood sugar was forced to constantly adjust to these conditions. For people with diabetes, increased blood sugar is a problem itself since they can not produce the extra insulin to keep blood sugar.
The good news, sports and nature of relaxation other stress management techniques can help us to control blood sugar levels.
In research done by experts from Duke University on 100 patients blood sugar stress management classes, known after a year of their blood sugar levels stay awake and risk of diabetic complications was reduced.
The study respondents stress management classes which include muscle relaxation, if the breath, and learn to have positive thoughts.
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Posted in generative disease | 
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